| ”There are a number of pieces involved in bringing sexed semen for A.I. to commercialization,” notes Mervyn Jacobson, president and CEO of XY Inc. The company holds exclusive global rights to the sperm-sorting license in non-human mammals. The privately held company was formed in 1996 as a joint venture of the Colorado State University Research Foundation and Cytomation Inc. of
Fort Collins, Colorado. It’s expanded its scope over the past three years to include international stakeholder, markets and all relevant livestock species. ”We’ve filed several patents in relation to all aspects of the technology and are putting the jigsaw puzzle together,” Jacobson says. Eventually he anticipates about 300 commercial licenses to be sold worldwide.
In the meantime, researchers have successfully bred several generations of cattle using the processes. “The true litmus test was to send the knowledge to a far-distant place and let someone else also achieve the same success,” says Jacobson. “We sent semen sexing
know-how -- we didn’t do it for them -- to our partners in England and they replicated our results.” Last May, several heifer cows were born in the United Kingdom using A.I. and preconception semen sexing technology, marking the first births of their kind outside the United States.
The next challenge, he says, is to gear up for mass use of the technology. “What we need now is repeatable proof on large numbers of animals. We’re going to prove it works again and again and again.”
Nearly 1,000 U.S. heifers have been bred A.I. with sexed semen to date.
Yet that’s not enough replication to satisfy the researchers. Large XY Inc. breeding field trials are planned for this year with 10,000 females in England and 5,000 females in the United States. The results are expected to provide significant research documentation on factors like pregnancy rates, abnormal offspring rates and actual sex-selection rates.
Current sexed-semen accuracy is tagged at 90%. Researchers are working at improving the fertility to greater than 90% of fertility of unsexed semen and using lower sperm numbers per dose. They’re also checking in refreezing the semen after sexing, adding even greater distribution opportunities.
“This technology makes the most sense economically if it’s used for millions of cows annually,” says Seidel. Perhaps that’s the best answer to whether the technology will be available for a $10 premium or if the cost will be significantly higher.

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